List 5 likely causes for the following coagulation profile.

Test

Value

Normal Range

PT*

35.4 Sec

12.0 - 15.0

INR*

3.5

0.8 - 1.1

APTT*

>170.0 Sec

25.0 - 37.0

FIBRINOGEN*

0.9 G/L

2.20 - 4.30

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College Answer

1)  DIC
2)  Primary fibrinolysis
3)  Dilutional coagulopathy from massive transfusion
4)  Post thrombolysis
5)  Snake bite

Discussion

This question is identical to Question 30.2 from the first paper of 2010.