In a suspected case of autoimmune encephalitis:
a) List the investigations needed, and explain why they are required. (50% marks)
b) Outline a specific management plan for proven autoimmune encephalitis and its common complications. Do not include resuscitation in your answer. (50% marks)
Not available.
a) Investigations listed here are partly to to confirm the diagnosis of autoimmune encephalitis, and partly to exclude other competing differentials.
CT brain
LP and CSF analysis
Peripheral blood tests
Imaging
Neurophysiology
Other tissues/fluids
b)
Management options for autoimmune encephalitis, and their complications:
Dalmau, Josep, and Myrna R. Rosenfeld. "Autoimmune encephalitis update." Neuro-oncology 16.6 (2014): 771-778.
Venkatesan, Arun, and Romergryko G. Geocadin. "Diagnosis and management of acute encephalitis: A practical approach." Neurology: Clinical Practice 4.3 (2014): 206-215.
Granerod, J., et al. "Causality in acute encephalitis: defining aetiologies." Epidemiology & Infection 138.6 (2010): 783-800.
Venkatesan, Arun. "CLINICAL APPROACH TO ACUTE ENCEPHALITIS." (2017).
Singh, Tarun D., Jennifer E. Fugate, and Alejandro A. Rabinstein. "The spectrum of acute encephalitis: causes, management, and predictors of outcome." Neurology 84.4 (2015): 359-366.