A two-week-old baby is brought to your general intensive care unit in extremis, pending transfer to a paediatric centre. The baby was born at term and discharged well on day 5 of life. For the past three days the baby has had progressive tachypnoea, lethargy and failure to feed, and has now presented after a seizure. The baby has been intubated in the emergency department.
Blood gas results taken breathing room air prior to intubation are below:
|
Parameter |
Patient |
Reference |
|
pH |
7.04* |
7.35 - 7.45 |
|
pCO2 |
14 mmHg (1.9 kPa) * |
35 – 45 (4.6 – 6.0) |
|
pO2 |
80 mmHg (10.5 kPa) |
|
|
Bicarbonate |
5 mmol/L* |
22-28 |
|
Lactate |
8 mmol/L* |
<2 |
|
Glucose |
0.9 mmol/L* |
3.5-6.1 |
|
White cell count |
14.7 x 109/L* |
4.0-11.0 |
|
Alanine aminotransferase (ALT) |
1600 U/L* |
10-55 |
|
Aspartate aminotransferase (AST) |
2200 U/L* |
10-40 |
a) List the likely differential diagnoses for this patient. (2 marks)
b) Outline your assessment to differentiate between these diagnoses. (3 marks)
c) Outline the management of this patient. (5 marks)
Syllabus topic/section:
2.1.17 Paediatrics: L2
Discussion:
Candidates who did well on this question were able to formulate a list of differentials, provide an assessment to help differentiate between the answers listed in part a), and then provide a general and specific plan of management. Some candidates were able to efficiently tabulate appropriate parts of their answer. Answers that included structure and a clear management plan of the listed abnormalities (e.g. hypoglycaemia) received more marks, as did those that referenced frequent liaison with a paediatric centre and specific treatments such as prostaglandin for potential duct dependent cardiac lesions.
Answers that did not attract as many marks omitted detail in part c) (50% of total marks for the question) Candidates should be aware of the marks allocated to different parts of each question and prioritise their timing accordingly for maximum time value. Some answers omitted important details such as omission of non- accidental injury (NAI) as a DDx in part a) and/or liaison with a paediatric centre. Some candidates also wrote detailed intubation specifics which did not attract marks as the stem outlined the intubation was already complete.
This is almost identical to Question 10 from the first paper of 2015, except in 2015 it was still ok to instruct the exam candidates to "list, in broad terms", whereas these days we use more meaningful language.
a) Systematically:
What could this mean?
b) Assessment:
|
History
|
Examination
|
Investigations
|
c) Management:
Approach to management, which is very generic:
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