Pharmacokinetics

Context sensitive half time using the example of opioids

Factors which influence gastrointestinal drug absorption

Effect of critical illness on pharmacokinetics

Bioavailability and the factors which affect it

Clearance, hepatic extraction ratio and the role of the liver in drug clearance

Volume of distribution: definition, measurement and factors affecting it

The significance of protein binding in pharmacology

Fentanyl vs remifentanil: a discussion of context-sensitive half time.

Bioavailability, and the factors which affect it

Role of the liver in pharmacokinetics: hepatic clearance and Phase I/II reactions

Factors which influence renal drug clearance: drug characteristics

Volume of distribution, and factors that influence it.

Factors affecting drug absorption from the gastrointestinal tract

The effects of critical illness on drug pharmacokinetics

Pharmacokinetics in obesity

Half-life of drugs

Renal clearance of drugs, and the effect of this on dosing

Pharmacokinetics in the elderly

Bioavailability and factors which influence it

Renal drug clearance

First order, zero order and non-linear elimination kinetics

Maintenance dose and loading dose; and the factors which affect them

Renal drug clearance

Interpreting the measurement of plasma drug concentrations