The focus of this viva is Evidence Based Medicine.
Please read this modified abstract.
High-Flow Nasal Oxygen vs Noninvasive Positive Airway Pressure in Hypoxemic Patients After Cardiothoracic Surgery
OBJECTIVE: To determine whether high-flow nasal oxygen therapy (HFNO2) was not inferior to BiPAP for preventing or resolving acute respiratory failure after cardiothoracic surgery.
DESIGN: Multicenter, randomized, non-inferiority trial
PARTICIPANTS: 830 of 3217 eligible patients who had undergone cardiothoracic surgery with acute respiratory failure (failure of a spontaneous breathing trial or successful breathing trial but failed extubation) or were deemed at risk for respiratory failure after extubation due to preexisting risk factors.
INTERVENTIONS: Patients were randomly assigned to receive HFNO2 delivered continuously (flow 50 L/min, FiO2 0.5) or BiPAP delivered with a full-face mask for at least 4 hours per day (PSV 8 cm H2O, PEEP 4 cm H2O, FiO2 0.5)
(Statistics and Interpretation of Evidence) - Pass rate ; highest mark .