Compare and contrast the pharmacology of noradrenaline and vasopressin
This was best answered using a table.
The main points expected for a pass were
- Both are naturally occurring substances
- Direct acting via receptors
- Mechanisms by which both increase mean arterial pressure
- Uses in Intensive Care, septic shock, vasodilatory shock and diabetes insipidus.
- Side effects related to intense vasoconstriction and for vasopressin possible coronary ischaemia and sodium and water retention