Outline the major clotting factors and steps in the haemostasis pathway (70% marks). Outline the mechanism of action of thrombolytics (30% marks).
Most candidates exhibited a structural approach with reasonable understanding of
the pharmacology of atropine although there was a lack of precision (anticholinergic
is correct, competitive muscarinic antagonist is more precise). Some answers did not
contrast glycopyrrolate adequately. The phrase ‘hepatic metabolism, renal excretion’
needed to be accompanied with detail if marks were to be awarded.
Recommended sources: Goodman and Gillman, The Pharmacological Basis of
Therapeutics, Chp 7