Outline the principles of compatibility testing of blood for transfusion.

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College Answer

There was a reasonable knowledge of the basics of ABO antigens and antibodies by most
candidates. However, many answers seemed to lack perspective of the steps performed in the
laboratory to improve immunological safety of transfusion. For a good answer it was expected that
candidates also discuss the basis to serological testing and antibody screening.
Syllabus: J2a, J2a2i
References: Guyton Textbook of Physiology Chp 32 and 35, Australian Red cross Transfusion
Medicine manual