Describe the pharmacology of magnesium sulphate.

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College Answer

Magnesium is a commonly administered agent within Intensive Care practice. Candidates 
performed poorly because of a lack of sufficient knowledge and a failure to structure their 
answer. For a good answer candidates were expected to mention that Magnesium comes as an 
inorganic sulphate, acts as a cofactor for a vast number of reactions, can be given orally (poor 
absorption) as well as intravenously, renal excretion with a low threshold. 

Recommended sources: Rang and Dale Pharmacology Pg 388; Katzung Basic and Clinical 
Pharmacology, Pg 244.