Describe the pharmacology of magnesium sulphate.
Magnesium is a commonly administered agent within Intensive Care practice. Candidates
performed poorly because of a lack of sufficient knowledge and a failure to structure their
answer. For a good answer candidates were expected to mention that Magnesium comes as an
inorganic sulphate, acts as a cofactor for a vast number of reactions, can be given orally (poor
absorption) as well as intravenously, renal excretion with a low threshold.
Recommended sources: Rang and Dale Pharmacology Pg 388; Katzung Basic and Clinical
Pharmacology, Pg 244.