Outline the physiological detection and response to an acute decrease in PaO2
Candidates were expected to focus on the physiology (including mechanisms) involved with
detection of hypoxia (e.g. peripheral chemoreceptor stimulation) as well as response.
Examples of response included sympathetic stimulation, the respiratory centre and organ
specific (e.g. cardiac, CNS, blood, cellular, etc) responses. This topic is well covered within a
number of fundamental texts, in particular, Nunn’s Respiratory Physiology. In general
candidates’ answers were not “broad” enough, lacked detail and were too focused on