Question 12

Outline the pharmacology of vancomycin

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College Answer

A basic and fundamental pharmacology question which required candidates to present their 
answer in a coherent fashion, as well as demonstrate sufficient knowledge. Candidates were 
expected to mention spectrum and mechanism of action, pharmacokinetics (including dose, 
distribution, elimination, etc) and adverse effects, activity profile e.g. time-dependent, 
antimicrobial activity depends on the duration that the serum drug concentration exceeds 
the minimum inhibitory concentration (MIC) of the target organism and not concentration