Describe the biochemical abnormalities, and the mechanisms by which they arise, that may be observed in a patient who is taking frusemide.

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College Answer

This was a relatively straightforward question with marks available for listing the 
abnormality and then discussing its origin. Many candidates simply listed an abnormality or 
confused the direction of electrolyte change. Few candidates went beyond hypokalaemia, 
hyponatraemia and hypochloraemia. Several candidates gave confused answers as to the 
mechanism(s) or drew pictures of a tubule with directional arrows for electrolytes with 
inadequate explanation. Some candidates simply ran out of time and wrote very little – this 
is a pity as a list would have generated marks. Candidates are reminded to practise the 
exams to time and attempt all questions.