Compare and contrast the mechanism of action, pharmacokinetics, adverse effects and  monitoring of effect of dabigatran and warfarin.

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College Answer

Most candidates were able to provide some details about warfarin however dabigatran was 
less well known. The syllabus provides a guide to depth of knowledge required for listed drugs 
and so more detail was expected for Warfarin as a class “A” drug than was expected for 
dabigatran (a class “C” drug). It was however expected that candidates would provide more 
than just generalisations regarding “hepatic metabolism and renal excretion” when applied to 
both agents that actually have different modes of elimination.