Describe the neural integration of vomiting. (60% of marks)

Describe the pharmacology of ondansetron. (40% of marks)

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College Answer

Candidates who failed the question did not answer the actual question. They did not discuss 
the neural integration but instead listed various inputs into the CTZ and vomiting centre. It 
was expected candidates could detail the pathways involved (afferent and efferent limbs) and 
describe the relationship with the coordinating centres. For example, afferent pathways to 
the vomiting centre include stretch and chemoreceptors located throughout the GIT via vagal 
and sympathetic nerves, pharyngeal touch receptors via glossopharyngeal nerves etc. Again 
structuring pharmacology answers was often poor.