Describe the pharmacology of oxygen
Use of a general "pharmacology" structure to answer this question would help avoid significant
omissions such as only discussing pharmacokinetics or only discussing pharmacodynamics.
Oxygen has a well described list of pharmacodynamics effects that includes, cardiovascular,
respiratory and central nervous system effects. Candidates’ knowledge of the pharmaceutics was
limited for a routine drug. It was expected candidates would mention the potential for oxygen
toxicity including a possible impact on respiratory drive in selected individuals, retrolental
fibroplasia and seizures under some circumstances.
Many candidates did not answer the question asked, and instead focussed on the physiology of
oxygen delivery and binding of oxygen to haemoglobin