Outline the fate of the triglyceride component of orally ingested fat
Triglycerides (TGs) consist of a 3 carbon glycerol backbone with 3 fatty acids attached. It was
expected candidates would detail the fate from digestion and absorption, through distribution to
storage and metabolism. Most candidates knew the absorptive processes very well but
knowledge of TGs fate once it was packaged into a chylomicron was lacking. Some detail was
expected on the passage to the liver via the portal circulation, packing and unpacking and
distribution to the body. Very few candidates mentioned appropriate hormones and enzymes,
target cells or ketogenesis. Some discussion was expected on the possible fate of acetyl
Co A. Comment on the synthesis of lipids and the existence of essential fatty acids gained
additional marks.