Question 6

Outline the physiology of pancreatic secretion (80% of marks) and outline the pharmacology of octreotide (20% of marks).

[Click here to toggle visibility of the answers]

College Answer

An outline of exocrine function should have included the sources of secretions, secretions 
involved in the digestion of proteins, carbohydrates and fats, the roles of trypsin inhibitors and 
bicarbonate secretion and the regulation of enzyme and bicarbonate secretion.” Knowledge 
of endocrine physiology was good whereas the depth of knowledge regarding exocrine 
function was generally shallow with many errors. 
Only some general facts around the pharmacology of octreotide were required to pass this 
section of the question. Responses revealed limited knowledge and contained many errors