Describe the ideal sedative agent for an Intensive Care patient (50% of marks). How 
does midazolam compare to this (50% of marks)? 

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College Answer

Candidates who had a structured approach (i.e. pharmaceutical, pharmacokinetic, 
pharmacodynamic) provided more content and scored higher. Candidates who also 
approached pharmacodynamic effects in an organ system based approach scored higher. 
Relating a pharmacokinetic property of midazolam (e.g. volume of distribution or half-life) to a 
un/desirable attribute e.g. offset of action and accumulation displayed a greater understanding 
of the question. For many candidates, the description of an ideal drug contained more detail 
and candidates were not able to adequately state how midazolam compares.