Describe the ideal sedative agent for an Intensive Care patient (50% of marks). How
does midazolam compare to this (50% of marks)?
Candidates who had a structured approach (i.e. pharmaceutical, pharmacokinetic,
pharmacodynamic) provided more content and scored higher. Candidates who also
approached pharmacodynamic effects in an organ system based approach scored higher.
Relating a pharmacokinetic property of midazolam (e.g. volume of distribution or half-life) to a
un/desirable attribute e.g. offset of action and accumulation displayed a greater understanding
of the question. For many candidates, the description of an ideal drug contained more detail
and candidates were not able to adequately state how midazolam compares.