Describe the endocrine functions of the kidney.
It was expected that candidates would discuss the major hormones produced (or activated) by the kidney. These included erythropoeitin, renin and calcitriol. Good answers included the following: the area where the hormone is produced or modified; stimuli for release; factors which inhibit release; and the subsequent actions / effects. Marks were not awarded for hormones that act on the kidney
Acharya, Vinay, and Juan Olivero. "The kidney as an endocrine organ." Methodist DeBakey cardiovascular journal 14.4 (2018): 305.
Henderson, Jenny, and Ian W. Henderson. "The endocrine functions of the kidney." Journal of Biological Education 28.4 (1994): 245-254.
Souma, Tomokazu, Norio Suzuki, and Masayuki Yamamoto. "Renal erythropoietin-producing cells in health and disease." Frontiers in physiology 6 (2015): 167.
Pagel, H., W. Jelkmann, and C. Weiss. "Erythropoietin production in the isolated perfused kidney." Biomedica biochimica acta 49.2-3 (1990): S271-4.
Jelkmann, Wolfgang. "Regulation of erythropoietin production." The Journal of physiology 589.6 (2011): 1251-1258.
Jelkmann, Wolfgang EB, et al. "Inhibition of erythropoietin production by cytokines: implications for the anemia involved in inflammatory states." Annals of the New York Academy of Sciences 718.1 (1994): 300-311.
Sungaran, R., B. Markovic, and B. H. Chong. "Localization and regulation of thrombopoietin mRNA expression in human kidney, liver, bone marrow, and spleen using in situ hybridization." Blood, The Journal of the American Society of Hematology 89.1 (1997): 101-107.
Stockelberg, D., et al. "Plasma thrombopoietin levels in liver cirrhosis and kidney failure." Journal of internal medicine 246.5 (1999): 471-475.
Forssmann, Wolf-Georg, Markus Meyer, and Kristin Forssmann. "The renal urodilatin system: clinical implications." Cardiovascular research 51.3 (2001): 450-462.
Norman, Anthony W. "From vitamin D to hormone D: fundamentals of the vitamin D endocrine system essential for good health." The American journal of clinical nutrition 88.2 (2008): 491S-499S.
Rabkin, R., A. H. Rubenstein, and J. A. Colwell. "Glomerular filtration and proximal tubular absorption of insulin 125 I." American Journal of Physiology-Legacy Content 223.5 (1972): 1093-1096.
Davidson, Warren D., Peter D. Springberg, and Newell R. Falkinburg. "Renal extraction and excretion of endogenous gastrin in the dog." Gastroenterology 64.5 (1973): 955-961.