Compare and contrast amiodarone and digoxin.

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College Answer

Most candidates had a good structure for answering this question; a table was commonly used. Marks were awarded for indications and an explanation of the mechanism of action of both drugs, which was generally well explained. The pharmacodynamic effects were often listed in a general manner and more detail would have achieved a higher mark, including a list of the ECG effects. Some detail on the pharmacokinetics and adverse effects of the drugs was expected and this section was generally well answered. Better answers noted digoxin levels and potential drug interactions.


This questiuon is virtually identical to Question 22 from the second paper of 2010.