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  1. Deranged Physiology
  2. CICM Primary Exam
  3. Required Reading
Renal system
Theoretical Foundations of Renal Replacement Therapy
Diffusion as a mechanism of solute removal
Diffusion in the counter-current dialysis circuit
Ultrafiltration as a mechanism of fluid removal
Filtration fraction as a measure of ultrafiltration
Convection as a mechanism of solute removal
Physical and chemical characteristics of dialysis membranes
Properties of dialysate and replacement fluid
Pre- and post-filter replacement fluid
Practical Aspects of Renal Replacement Therapy
Vascular access for urgent dialysis
Anatomy of the extracorporeal dialysis circuit
Anticoagulation of the dialysis circuit
Strategies to extend the lifespan of the dialysis circuit
Clearance of urea and uraemic toxins
Strategies used to enhance solute clearance
Factors which influence drug dosing in dialysis
Modalities of Renal Replacement Therapy
An overview of the modalities of renal replacement therapy
Conventional intermittent haemodialysis (IHD)
Continuous renal replacement therapy (CRRT)
Slow low efficiency daily dialysis (SLED)
High flux techniques and unusual filter membranes
Clinical Applications of Dialysis
Pathophysiological consequences of chronic renal failure
Indications for dialysis
Determining the dose of dialysis
Complications of Dialysis
Unintended consequences of renal replacement therapy
Haemoperfusion for Blood Purification
Blood purification by adsorption
Selectivity of sorbents and efficacy of adsorption
Indications for haemoperfusion
Complications unique to haemoperfusion

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