Viva 8

This Viva will examine your knowledge of the pharmacokinetics of thiopentone.
What factors determine how quickly a patient becomes unconscious with an induction dose 
of thiopentone? Subsequent questions explored knowledge of serum concentration vs time curves and the information derived from them, volume of distribution (factors that affect it and how it is 
measured), clearance (definition, calculation, relationship to volume of distribution), 
elimination (first and zero order) and half-life.