A free online resource for Intensive Care Medicine.
An unofficial Fellowship Exam (CICM Part 2) preparation resource.
Deranged Physiologyis a slowly growing archive of discussions and study notes relevant (or if not relevant, then at least interesting) to the practice of intensive care medicine. The content provides an introduction to the fundamental themes in intensive care: mechanical ventilation, vasopressors, electrolyte management, hemodynamic monitoring, dialysis, and so forth. Attention is directed at equipment in intensive care, and there are attempts to revisit interesting pharmacology and physiology. The aim of this resource is to supplement the bedside teaching of senior staff, and to consolidate resources for intensive care trainees in the initial stages of their training.
There is a good article by Hegewald & Crapo which summarises the respiratory physiology of pregnancy in clear and concise terms. On the basis of this article, I have tried to compile a list of the relevant changes:
GIVE trigger: GCS under 5, intubated, ventilated, and with end-of-life discussions in progress.
In NSW, the two doctors determining brain death cant be involved in the tissue removal or the care of the organ recipient, and must have practiced medicine for at least 5 of the last 8 years. Furthermore, one of them must be a designated specialist in that hospital.
This is the abnormal physiological state which occurs when whole-body ischaemia is followed by whole-body reperfusion.
In summary, it is a systemic inflammatory state which resembles every other form of vasodilatory shock; the degree of organ dysfunction depends on the sensitivity of those organs to ischaemia, and the duration of ischaemic time.