So, your PaCO2 is, oh say 150mmHg. So what. What could go wrong?
Consequences of Respiratory Acidosis |
Consequences of Respiratory Alkalosis |
Respiratory consequences:
Cardiovascular consequences:
Neurological consequences
Electrolyte derangement
|
Respiratory consequences
Cardiovascular consequences
Neurological consequences
|
Interestingly, none of this has ever made it into the fellowship paper. One might suppose that such fundamental concepts are better interrogated in the primary exam. For those who were for whatever reason exempted from this great barrier, apocryphal pages are available in the section concerned with acid-base disturbances. Specific chapters offer detailed digressions regarding physiological effects of carbon dioxide, buffering in acute respiratory acid-base disturbances and the physiology of carbon dioxide storage and transport.
Clowes Jr, George HA, A. L. Hopkins, and Fiorindo A. Simeone. "A comparison of the physiological effects of hypercapnia and hypoxia in the production of cardiac arrest." Annals of surgery 142.3 (1955): 446.
Giebisch, Gerhard, et al. "The extrarenal response to acute acid-base disturbances of respiratory origin." Journal of Clinical Investigation 34.2 (1955): 231.
Foster, Guy T., Nostratola D. Vaziri, and C. S. Sassoon. "Respiratory alkalosis."Respiratory care 46.4 (2001): 384-391.