Sepsis and Infections

Sepsis and Septic Shock
Resuscitation of the Septic Shock Patient
Critique of the Surviving Sepsis guidelines
Critique of early goal-directed therapy protocol for sepsis
Fluid resuscitation for septic shock
Noradrenaline in resuscitation of septic shock
Vasopressin in resuscitation of septic shock
Inotropes in resuscitation of septic shock
Corticosteroids in septic shock
Management of super-refractory septic shock
Significance of the endothelial glycocalyx
Critique of obsolete definitions for sepsis and SIRS
Critique of the modern definitions for sepsis (Sepsis-III)
The difficulty in making a diagnosis of sepsis
Biomarkers of sepsis

Multiple organ dysfunction syndrome
Pathogenesis of multi-organ system failure in sepsis

Rarer infections with specific ICU considerations
Necrotising soft tissue infections
Streptococcal toxic shock and other toxic shock syndromes
Bacterial and virial meningitis and encephalitis
Pneumococcal meningitis
Arboviral encephalitis
Infective endocarditis
Malaria
Tetanus
Melioidosis
Viral haemorrhagic fever- Dengue and Ebola
Cryptococcus

Antimicrobial use in the ICU
Pharmacokinetics of antibiotics in critical illness
Antibiotic dosing in renal failure
Antibiotic dosing during dialysis
Kill characteristics of antibiotic agents
Antibiotic dosing as continuous infusion
Causes of antibiotic treatment failure
General principles and common errors of antibiotic use
The minimum inhibitory concentration (MIC)
Post-antibiotic effect
Antibiotic agents classified by mechanism of action
Specific antibiotic choices for selected pathogens
Pharmacology of antifungal agents

Deuterocanon
Microorganisms organised by Gram stain and metabolism
Acronymous organisms: ESCAPPM and HACEK
Aspergillosis and other invasive fungal infections
Candida - albicans and non-albicans
H1N1 "Swine Flu" influenza, SARS and MERS
COVID-19
Cytomegalovirus
Varicella zoster virus and VZV pneumonia
Tuberculosis
Human immunodeficiency virus (HIV) and AIDS
Coagulase-negative Staphylococci
The meaning of positive blood cultures
Staphylococcus aureus bacteraemia
Legionella
Pneumocystis jirovecii
Leptospirosis
Infectious and non-infectious causes of fever
Meningococcal sepsis
Differential diagnosis of purpura fulminans
Spontaneous bacterial peritonitis
Community-acquired pneumonia
Sepsis in the post-splenectomy patient
Sepsis in the bone marrow transplant recipient
Sepsis in the heart and lung transplant recipient
Sepsis in the neutropenic host
Sepsis in the peripartum and postpartum period
Cellulitis
The staff member with a needle stick injury