Offered below is an organised list of summaries on the topic of pharmacology and toxicology from the Critical Care Compendium, courtesy of LITFL. Given the mixture of topics, the ideal audience for this material is the final stage exam candidate pursuing dual CICM and ACEM fellowship qualifications.
Pharmacology and Toxicology in the Critical Care Compendium
Toxicology and pharmacology broadly
Antidotes and forced enhanced clearance
Overdose favourites
Toxidromes
Withdrawal syndromes
Anaesthetic and analgesic agents
Anticoagulants and procoagulants
- Protamine
- Prothrombinex
- cleaxane, enoxaparin
- desmopressin, DDAVP
- alteplase, rTPA
- aprotinin
- low molecular weight heparin, LMWH,
- Tenecteplase, TNK-tPA
- Factor VIIa, seven, 7
- heparin, unfractionated, UFH
- ticlodipine
- tranexamic acid, TXA
- warfarin
Antiplatelet agents and NSAIDs
Gastrointestinal pharmacopoeia
Antihypertensives and diuretics
Vasoactive drugs
Antiarrhythmics
Antibiotics
Miscellaneous substances of toxicological interest
- Polonium
- Activated protein C, drotrecogin alpha
- Ciguatera poisoning
- Marine envenoming, jellyfish, octopus, fish
- Mushroom toxicity, poisoning, fungi
- Plant toxicity, poisoning, herbal
- Scombroid poisoning, fish
- Snakebite envenoming
- Spider envenoming
- Tick paralysis, ixodid hard tick
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